Properties
- CAS Number
- 219580-11-7
- Formula
- C28H41N7O3
- Molecular Weight
- 523.7 g/mol
- IUPAC Name
- 1-tert-butyl-3-[2-[4-(diethylamino)butylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea
- InChI Key
- DXCUKNQANPLTEJ-UHFFFAOYSA-N
Also Known As
Description
PD173074 is a member of the class of ureas that is 1-tert-butylurea in which one of the hydrogens attached to N3 is substituted by a pyrido[2,3-d]pyrimidin-7-yl group, which is itself substituted at positions 2 and 6 by a 4-(diethylamino)butyl]amino group and a 3,5-dimethoxyphenyl group, respectively. It is a FGF/VEGF receptor tyrosine kinase inhibitor. It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and a fibroblast growth factor receptor antagonist. It is an aromatic amine, a pyridopyrimidine, a member of ureas, a tertiary amino compound, a dimethoxybenzene and a biaryl. It is functionally related to a PD-166866.
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