2-methyl-6-(2-phenylethyny… (CAS 219911-35-0)

About 2-methyl-6-(2-phenylethynyl)pyridine;hydrochloride

2-methyl-6-(2-phenylethynyl)pyridine;hydrochloride (CAS 219911-35-0) is a chemical compound with the molecular formula C14H12ClN and a molecular weight of 229.7 g/mol. It has an InChIKey of PKDHDJBNEKXCBI-UHFFFAOYSA-N.

Properties

2-methyl-6-(2-phenylethynyl)pyridine;hydrochloride molecular structure

CAS Number: 219911-35-0
Formula: C14H12ClN
Molecular Weight: 229.7 g/mol
IUPAC Name: 2-methyl-6-(2-phenylethynyl)pyridine;hydrochloride
InChI Key: PKDHDJBNEKXCBI-UHFFFAOYSA-N

Also Known As

2-methyl-6-(2-phenylethynyl)pyridine;hydrochloride is also known as MPEP hydrochloride, MPEP HCl, MPEP (Hydrochloride), MPEP hydrochloride?, 2-methyl-6-(phenylethynyl)pyridine hcl, PKDHDJBNEKXCBI-UHFFFAOYSA-N, among other names.

MPEP hydrochloride 2-methyl-6-(phenylethynyl)pyridine hydrochloride 6-Methyl-2-(phenylethynyl)pyridine hydrochloride UNII-AU9X845ZWM AU9X845ZWM DTXSID9043982 2-methyl-6-(phenylethynyl)pyridinium chloride 6-methyl-2-(phenylethynyl)pyridinium chloride CHEBI:64158 2-METHYL-6-(PHENYLETHYNYL)PYRIDINE, HYDROCHLORIDE

6-Methyl-2-(phenylethynyl)pyridine, hydrochloride Pyridine, 2-methyl-6-(phenylethynyl)-, hydrochloride Pyridine, 6-methyl-2-(phenylethynyl)-, hydrochloride PYRIDINE, 2-METHYL-6-(2-PHENYLETHYNYL)-, HYDROCHLORIDE (1:1) RefChem:88205 DTXCID5022564 MPEP HCl MPEP (Hydrochloride) MFCD02262119 SR-01000075996 MPEP hydrochloride? 2-methyl-6-(phenylethynyl)pyridine hcl EU-0100738 MLS002153163 SCHEMBL660360 orb1300627 orb1305394 CHEMBL1255868 SCHEMBL29394034 EX-A194 PKDHDJBNEKXCBI-UHFFFAOYSA-N Tox21_500738 HB0426 AKOS024456469 CCG-222042 CS-0793 FM64915 LP00738 NCGC00094081-01 NCGC00261423-01 AC-32870 AC-35261 AS-55809 HY-14609 SMR001230657 DB-014655 T2497 T6598 2-methyl-6-(phenylethynyl)pyridinehydrochloride 2-Methyl-6-phenylethynyl-pyridine hydrochloride

Description

2-methyl-6-(phenylethynyl)pyridine hydrochloride is a hydrochloride salt obtained by reaction of 2-methyl-6-(phenylethynyl)pyridine with one equivalent of hydrochloric acid. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. It has a role as an anxiolytic drug and a metabotropic glutamate receptor antagonist. It contains a 2-methyl-6-(phenylethynyl)pyridinium(1+).

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