4-[1,3-bis(4-hydroxyphenyl… (CAS 263717-53-9)

About 4-[1,3-bis(4-hydroxyphenyl)-4-propylpyrazol-5-yl]phenol

4-[1,3-bis(4-hydroxyphenyl)-4-propylpyrazol-5-yl]phenol (CAS 263717-53-9) is a chemical compound with the molecular formula C24H22N2O3 and a molecular weight of 386.4 g/mol. It has an InChIKey of IOTXSIGGFRQYKW-UHFFFAOYSA-N.

Properties

4-[1,3-bis(4-hydroxyphenyl)-4-propylpyrazol-5-yl]phenol molecular structure

CAS Number: 263717-53-9
Formula: C24H22N2O3
Molecular Weight: 386.4 g/mol
IUPAC Name: 4-[1,3-bis(4-hydroxyphenyl)-4-propylpyrazol-5-yl]phenol
InChI Key: IOTXSIGGFRQYKW-UHFFFAOYSA-N

Also Known As

4-[1,3-bis(4-hydroxyphenyl)-4-propylpyrazol-5-yl]phenol is also known as propyl pyrazole triol, PROPYLPYRAZOLETRIOL, PPT, PPT trisphenol compound, Tocris-1426, Lopac-H-6036, among other names.

propyl pyrazole triol PROPYLPYRAZOLETRIOL DTXSID9040392 RefChem:1097032 DTXCID7020392 PPT 4,4',4''-(4-propyl-1H-pyrazole-1,3,5-triyl)triphenol 1,3,5-Tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole Phenol, 4,4',4''-(4-propyl-1H-pyrazole-1,3,5-triyl)tris- 0T83Y6JZPF

4,4',4''-(4-propyl-(1H)-pyrazole-1,3,5-triyl)trisphenol 1,3,5-tris(4-hydroxyphenyl)-4-propylpyrazole MFCD03453628 4,4',4''-(4-propylpyrazole-1,3,5-triyl)trisphenol 4,4',4''-(4-Propyl-[1H]-pyrazole-1,3,5-triyl)trisphenol 4-(1,5-bis(4-hydroxyphenyl)-4-propyl-1,2-dihydro-3H-pyrazol-3-ylidene)cyclohexa-2,5-dien-1-one PPT trisphenol compound SR-01000075913 NCGC00015511-01 Tocris-1426 4-[2,5-BIS(4-HYDROXYPHENYL)-4-PROPYLPYRAZOL-3-YL]PHENOL Lopac-H-6036 UNII-0T83Y6JZPF 4-Propyl-1,3,5-tri((4-hydroxy)phenyl)pyrazole Lopac0_000575 MLS001056593 SCHEMBL426190 CHEMBL441282 GTPL2819 orb1307858 CHEBI:64110 CHEBI:92007 HMS2233O06 HMS3261D12 HMS3267J14 HMS3412O22 HMS3650I12 HMS3676O22 Tox21_500575 BDBM50398935 HB2499 AKOS024456590 CCG-204664 LP00575 SDCCGSBI-0050557.P002 NCGC00015511-02 NCGC00015511-03 NCGC00015511-04 NCGC00015511-05 NCGC00015511-06

Description

4,4',4''-(4-propylpyrazole-1,3,5-triyl)trisphenol is a pyrazole that is 1H-pyrazole bearing three 4-hydroxyphenyl substituents at positions 1, 3 and 5 as well as a propyl substituent at position 4. Potent, subtype-selective estrogen receptor agonist (EC50 ~ 200 pM); displays 410-fold selectivity for ERalpha over ERbeta. Prevents ovariectomy-induced weight gain and loss of bone mineral density, and induces gene expression in the hypothalamus following systemic administration in vivo. It has a role as an estrogen receptor agonist. It is a member of pyrazoles and a member of phenols.

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