About 4-[3-cyclohexyl-5-(4-fluorophenyl)imidazol-4-yl]pyrimidin-2-amine;dihydrochloride
4-[3-cyclohexyl-5-(4-fluorophenyl)imidazol-4-yl]pyrimidin-2-amine;dihydrochloride (CAS 950912-80-8) is a chemical compound with the molecular formula C19H22Cl2FN5 and a molecular weight of 410.3 g/mol. It has an InChIKey of PSNKGVAXBSAHCH-UHFFFAOYSA-N.
Properties
Also Known As
4-[3-cyclohexyl-5-(4-fluorophenyl)imidazol-4-yl]pyrimidin-2-amine;dihydrochloride is also known as PF-670462 HCl, 950912-80-8 (HCl), PF670462 dihydrochloride, PF-670462 dihydrochloride, PF-670462 2HCl, among other names.
Description
PF-670462 is a hydrochloride salt resulting from the formal reaction of 3-[(3-chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine with 2 mol eq. of hydrogen chloride. It is a selective inhibitor of the delta- and -isoforms of casein kinase 1 (CK1delta and CK1). It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It contains a PF-670462 free base(2+).
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