5-(2,6-dichlorophenyl)-2-(… (CAS 209410-46-8)

About 5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one

5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one (CAS 209410-46-8) is a member of the pyrimidopyridazines class of chemical compounds with the molecular formula C19H9Cl2F2N3OS and a molecular weight of 436.3 g/mol. It has an InChIKey of VEPKQEUBKLEPRA-UHFFFAOYSA-N.

Properties

5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one molecular structure

CAS Number: 209410-46-8
Formula: C19H9Cl2F2N3OS
Molecular Weight: 436.3 g/mol
IUPAC Name: 5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one
InChI Key: VEPKQEUBKLEPRA-UHFFFAOYSA-N

Also Known As

5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one is also known as Neflamapimod, neflamapimodum, C19H9Cl2F2N3OS, Neflamapimod [USAN], Neflamapimod (USAN/INN), NEFLAMAPIMOD [INN], among other names.

Neflamapimod VX-745 5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido[1,6-b]pyridazin-6-one VRT-031745 TYL52QM320 VD-31745 VD-31,745 6H-Pyrimido[1,6-b]pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)thio]- 5-(2,6-Dichlorophenyl)-2-[(2,4-Difluorophenyl)sulfanyl]-6h-Pyrimido[1,6-B]pyridazin-6-One CHEBI:90528

5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido(1,6-b)pyridazin-6-one 5-(2,6-Dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-one 6H-Pyrimido(1,6-b)pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-((2,4-difluorophenyl)thio)- 5-(2,6-Dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyridazino[6,1-f]pyrimidin-6-one neflamapimodum 5-(2,6-dichlorophenyl)-2-((2,4-difluorophenyl)sulfanyl)-6H-pyrimido(1,6-b)pyridazin-6-one 5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyridazino(6,1-f)pyrimidin-6-one RefChem:832136 6H-pyrimido(1,6-b)pyridazin-6-one,5-(2,6-dichlorophenyl)-2-(phenylthio)- VX 745 VX745 C19H9Cl2F2N3OS Neflamapimod [USAN] 5-(2,6-dichlorophenyl)-2-(2,4-difluorophenylthio)-6H-pyrimido[1,6-b]pyridazin-6-one 5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)-thio)-6H-pyrimido[1,6-b]pyridazin-6-one 5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfanyl-pyrimido[1,6-b]pyridazin-6-one 5-(2,6-Dichlorophenyl)-2-[2,4-difluorophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-one 5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido[1,6-B]pyridazine-6-one 5-(2,6-DICHLOROPHENYL)-2-((2,4-DIFLUOROPHENYL)THIO)-6H-PYRIMIDO(1,6-B)PYRIDAZINE-6-ONE MFCD09834070 Kinome_3767 Neflamapimod (USAN/INN) NEFLAMAPIMOD [INN] UNII-TYL52QM320 MLS006010281 NEFLAMAPIMOD [WHO-DD] SCHEMBL156367 CHEMBL119385 GTPL5719 orb1301083 SCHEMBL29396525 BDBM15244 cid_3038525 NEFLAMAPIMOD (VX-745) DTXSID90175115 EX-A854 GLXC-05950 HMS3295M13 HMS3654L10 HMS3884M17

Description

VX-745 is a member of the class of pyrimidopyridazines that is 6H-pyrimido[1,6-b]pyridazin-6-one substituted at positions 2 and 5 by (2,4-difluorophenyl)sulfanyl and 2,6-dichlorophenyl groups respectively. It has a role as an anti-inflammatory drug, an apoptosis inducer and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is a dichlorobenzene, an aryl sulfide, a difluorobenzene and a pyrimidopyridazine.

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