CHEBI:63988

5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol

104422-04-0 C19H21NO2

Properties

CHEBI:63988 molecular structure
CAS Number
104422-04-0
Formula
C19H21NO2
Molecular Weight
295.4 g/mol
IUPAC Name
5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol
InChI Key
QBUVZVXIRYFENV-UHFFFAOYSA-N

Also Known As

Skf-77434 SKF 77434 SK&F 77434 XA99M7XZR5 J247.964H DTXSID3043817 1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)- 1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)- SKF-77,434 RefChem:183297

Description

N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol is a benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1, an allyl substituent at position 3 and two hydroxy substituents at positions 7 and 8. Selective dopamine D1-like receptor partial agonist (IC50 values are 19.7 and 2425 nM for binding to D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo. It has a role as a dopamine agonist. It is a member of catechols, a benzazepine and a tertiary amino compound. It is a conjugate base of a N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepinium-7,8-diol(1+).

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