6-[2-[[4-(2,4-dichlorophen… (CAS 252917-06-9)

About 6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile

6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile (CAS 252917-06-9) is a member of the aminopyrimidines class of chemical compounds with the molecular formula C22H18Cl2N8 and a molecular weight of 465.3 g/mol. It has an InChIKey of AQGNHMOJWBZFQQ-UHFFFAOYSA-N.

Properties

6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile molecular structure

CAS Number: 252917-06-9
Formula: C22H18Cl2N8
Molecular Weight: 465.3 g/mol
IUPAC Name: 6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile
InChI Key: AQGNHMOJWBZFQQ-UHFFFAOYSA-N

Also Known As

6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile is also known as laduviglusib, Laduviglusib [USAN], LADUVIGLUSIB [INN], Laduviglusib (USAN), Laduviglusib (GMP), CHIR-99021 (CT99021), among other names.

CHIR-99021 laduviglusib CHIR 99021 CT-99021 CT99021 6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile CHIR-911 CT 99021 Laduviglusib [USAN] CHR00921

6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile 234CMT4GK4 CHIR 911 CHR-00921 LADUVIGLUSIB [INN] CHEBI:91091 DTXSID90179931 3-Pyridinecarbonitrile, 6-((2-((4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl)amino)ethyl)amino)- Laduviglusib (USAN) 6-[(2-{[4-[2,4-Dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]NH}ethyl)NH]pyridine-3-CN 6-((2-((4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)pyridine-3-carbonitrile 6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl)NH)ethyl)NH)pyridine-3-CN 6-(2-((4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethylamino)pyridine-3-carbonitrile RefChem:798393 DTXCID50102422 809-015-4 CHIR99021 [2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile 6-((2-((4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile 6-[2-[4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino]ethylamino]pyridine-3-carbonitrile Laduviglusib (GMP) FX03 CHIR-99021 (CT99021) MFCD11846251 CHEMBL412142 CHIR 99021 Hydrochloride Salt 252917-06-9 (free base) GSK-3 Inhibitor XVI 6-(2-(4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino)ethylamino)nicotinonitrile 6-[(2-{[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile UNII-234CMT4GK4 C22H18Cl2N8 6-[(2-([4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile 6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino)ethyl)amino]pyridine-3-carbonitrile 6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile 65C Kinome_3785 Laduviglusib (Standard) SCHEMBL151139 SCHEMBL240280

Description

CHIR 99021 is a member of the class of aminopyrimidines that is 2-aminopyrimidine substituted at positions N2, 5 and 6 by (5-cyanopyridin-2-yl)ethyl, 4-methylimidazol-2-yl and 2,4-dichlorophenyl groups respectively. It has a role as an EC 2.7.11.26 (tau-protein kinase) inhibitor. It is a cyanopyridine, a diamine, a dichlorobenzene, a member of imidazoles, an aminopyridine, an aminopyrimidine and a secondary amino compound.

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