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6-fluoro-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine

1303420-67-8 C21H19F2N5O

About 6-fluoro-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine

6-fluoro-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine (CAS 1303420-67-8) is a chemical compound with the molecular formula C21H19F2N5O and a molecular weight of 395.4 g/mol. It has an InChIKey of NSMOZFXKTHCPTQ-UHFFFAOYSA-N.

Properties

6-fluoro-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine molecular structure
CAS Number
1303420-67-8
Formula
C21H19F2N5O
Molecular Weight
395.4 g/mol
IUPAC Name
6-fluoro-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine
InChI Key
NSMOZFXKTHCPTQ-UHFFFAOYSA-N

Also Known As

6-fluoro-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine is also known as PLX5622 free base, among other names.

PLX5622 6-Fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine PLX-5622 6-fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine 16A8IGR8L7 5-fluoro-N-[6-fluoro-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-2-methoxy-3-pyridinemethanamine 3-Pyridinemethanamine, 5-fluoro-N-(6-fluoro-5-((5-methyl-1H-pyrrolo(2,3-b)pyridin-3-yl)methyl)-2-pyridinyl)-2-methoxy- 5-Fluoro-N-(6-fluoro-5-((5-methyl-1H-pyrrolo(2,3-b)pyridin-3-yl)methyl)-2-pyridinyl)-2-methoxy-3-pyridinemethanamine 6-fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo(2,3-b)pyridin-3-yl)methyl)pyridin-2-amine RefChem:174940

Description

PLX5622 is a highly selective brain penetrant and orally active CSF1R inhibitor. PLX5622 allows for extended and specific microglial cells elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals. PLX5622 is mostly used in the way of feed free diet.

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