(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide

133550-30-8 C17H14N2O3

About (E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide

(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide (CAS 133550-30-8) is a chemical compound with the molecular formula C17H14N2O3 and a molecular weight of 294.3 g/mol. It has an InChIKey of TUCIOBMMDDOEMM-RIYZIHGNSA-N.

Properties

(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide molecular structure
CAS Number
133550-30-8
Formula
C17H14N2O3
Molecular Weight
294.3 g/mol
IUPAC Name
(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
InChI Key
TUCIOBMMDDOEMM-RIYZIHGNSA-N

Also Known As

(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide is also known as Tyrphostin B42, tyrphostin AG-490, Tyrphostin AG 490, Tyrphostin AG490, AG-490 (Tyrphostin B42), (E/Z)-AG490, among other names.

AG-490 Tyrphostin B42 AG 490 AG490 tyrphostin AG-490 alpha-Cyano-(3,4-dihydroxy)-N-benzylcinnamide C4UD8F8XJY n-benzyl-3,4-dihydroxy-benzylidenecyanoacetamide DTXSID5040960 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide

Description

Tyrphostin B42 is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid with the amino group of benzylamine. It has a role as a geroprotector, an antioxidant, an anti-inflammatory agent, an apoptosis inducer, an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor and a STAT3 inhibitor. It is a secondary carboxamide, a nitrile, a monocarboxylic acid amide, a member of catechols and an enamide.

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