N-[(E)-(3,4-dihydroxyphenyl)methylideneamino…

About N-[(E)-(3,4-dihydroxyphenyl)methylideneamino]-3-hydroxynaphthalene-2-carboxamide

N-[(E)-(3,4-dihydroxyphenyl)methylideneamino]-3-hydroxynaphthalene-2-carboxamide is a chemical compound with the molecular formula C18H14N2O4 and a molecular weight of 322.3 g/mol. It has an InChIKey of SYNDQCRDGGCQRZ-VXLYETTFSA-N.

Properties

N-[(E)-(3,4-dihydroxyphenyl)methylideneamino]-3-hydroxynaphthalene-2-carboxamide molecular structure

Formula: C18H14N2O4
Molecular Weight: 322.3 g/mol
IUPAC Name: N-[(E)-(3,4-dihydroxyphenyl)methylideneamino]-3-hydroxynaphthalene-2-carboxamide
InChI Key: SYNDQCRDGGCQRZ-VXLYETTFSA-N

Also Known As

N-[(E)-(3,4-dihydroxyphenyl)methylideneamino]-3-hydroxynaphthalene-2-carboxamide is also known as Dynasore, Dynamin Inhibitor I, Dynasore?, SYNDQCRDGGCQRZ-VXLYETTFSA-N, among other names.

Dynasore Dynamin Inhibitor I CHEBI:132754 DTXSID60420841 3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide RefChem:1084012 DTXCID60371687 Dynasore? 2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(3,4-dihydroxyphenyl)methylene]hydrazide MFCD00292551

N'-(3,4-Dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide CHEMBL1209885 N'-[(3,4-dihydroxyphenyl)methylidene]-3-hydroxynaphthalene-2-carbohydrazide SCHEMBL4570231 SCHEMBL29385895 SYNDQCRDGGCQRZ-VXLYETTFSA-N GLXC-04569 EMA44855 BDBM50323460 EBC-08516 HB1245 STK028329 AKOS000486035 AKOS026750233 CCG-267726 CS-1340 UPCMLD0ENAT5920180:001 NCGC00386289-01 NCGC00386289-03 NCGC00386289-08 3-hydroxy-N'-[(E)-(3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]naphthalene-2-carbohydrazide AC-32834 AS-74080 HY-15304 ST036482 SY068326 T1848 EN300-97658 N10862 BRD-K87718015-001-01-9 BRD-K87718015-001-02-7 Q27225640 Z49628777 N''-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide (E)-N'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide N'-[(E)-(3,4-dihydroxyphenyl)methylene]-3-hydroxy-2-naphthohydrazide N inverted exclamation mark -(3,4-Dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide N'-[(E)-(3,4-dihydroxyphenyl)methylidene]-3-hydroxynaphthalene-2-carbohydrazide N-[(1E)-2-(3,4-dihydroxyphenyl)-1-azavinyl](3-hydroxy(2-naphthyl))carboxamide N-[(E)-(3,4-dihydroxyphenyl)methyleneamino]-3-hydroxy-naphthalene-2-carboxamide

Description

Dynasore is a carbohydrazide resulting from the formal condensation of the hydrazone moiety of 3,4-dihydroxybenzaldehyde hydrazone with the carboxy group of 3-hydroxy-2-naphthoic acid. It is a cell-permeable, reversible noncompetitive inhibitor of the GTPase activity of dynamin 1 and 2 and Drp1 (mitochondrial), while exhibiting no significant effect against two other small GTPases, MxA and Cdc42. It has a role as an EC 3.6.5.5 (dynamin GTPase) inhibitor. It is a member of naphthols, a member of catechols, a hydrazide and a hydrazone. It is functionally related to a 3-Hydroxy-2-naphthoate.

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