tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate

208255-80-5 C23H26F2N2O4

About tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate

tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate (CAS 208255-80-5) is a chemical compound with the molecular formula C23H26F2N2O4 and a molecular weight of 432.5 g/mol. It has an InChIKey of DWJXYEABWRJFSP-XOBRGWDASA-N.

Properties

tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate molecular structure
CAS Number
208255-80-5
Formula
C23H26F2N2O4
Molecular Weight
432.5 g/mol
IUPAC Name
tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate
InChI Key
DWJXYEABWRJFSP-XOBRGWDASA-N

Also Known As

tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate is also known as dapt, GSI-IX, DAPT (GSI-IX), gamma-Secretase Inhibitor IX, DAPT (GMP), DAPT (peptide), among other names.

dapt GSI-IX CHEBI:86193 tert-butyl (2S)-2-(((2S)-2-((2-(3,5-difluorophenyl)acetyl)amino)propanoyl)amino)-2-phenylacetate RefChem:1082973 DAPT (GSI-IX) gamma-Secretase Inhibitor IX C23H26F2N2O4 MFCD04974585 tert-butyl (S)-2-((S)-2-(2-(3,5-difluorophenyl)acetamido)propanamido)-2-phenylacetate

Description

DAPT is a dipeptide consisting of alanylphenylglycine derivatised as a 3,5-difluorophenylacetamide at the amino terminal and a tert-butyl ester at the carboxy terminal. It is a gamma-secretase inhibitor. It has a role as an EC 3.4.23.46 (memapsin 2) inhibitor. It is a tert-butyl ester, a carboxylic ester, a difluorobenzene and a dipeptide.

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