About tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate
tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate (CAS 208255-80-5) is a chemical compound with the molecular formula C23H26F2N2O4 and a molecular weight of 432.5 g/mol. It has an InChIKey of DWJXYEABWRJFSP-XOBRGWDASA-N.
Properties
Also Known As
tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate is also known as dapt, GSI-IX, DAPT (GSI-IX), gamma-Secretase Inhibitor IX, DAPT (GMP), DAPT (peptide), among other names.
Description
DAPT is a dipeptide consisting of alanylphenylglycine derivatised as a 3,5-difluorophenylacetamide at the amino terminal and a tert-butyl ester at the carboxy terminal. It is a gamma-secretase inhibitor. It has a role as an EC 3.4.23.46 (memapsin 2) inhibitor. It is a tert-butyl ester, a carboxylic ester, a difluorobenzene and a dipeptide.
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