About 3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid (CAS 215543-92-3) is a chemical compound with the molecular formula C17H16N2O3 and a molecular weight of 296.32 g/mol. It has an InChIKey of JNDVEAXZWJIOKB-JYRVWZFOSA-N.
Properties
Also Known As
3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid is also known as SU 5402 (GMP), JNDVEAXZWJIOKB-JYRVWZFOSA-N, KDR Kinase Inhibitor, 5, compound 1 [PMID: 10602697], SU-5402, >=98% (HPLC), among other names.
Description
SU5402 is an oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 3-(2-carboxyethyl)-4-methyl-1H-pyrrol-2-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1. It has a role as a fibroblast growth factor receptor antagonist. It is a monocarboxylic acid, a member of pyrroles and a member of oxindoles. It is functionally related to a 3-methyleneoxindole.
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