FOM

3-[formyl(hydroxy)amino]propylphosphonic acid

66508-53-0 C4H10NO5P

Properties

FOM molecular structure
CAS Number
66508-53-0
Formula
C4H10NO5P
Molecular Weight
183.1 g/mol
IUPAC Name
3-[formyl(hydroxy)amino]propylphosphonic acid
InChI Key
GJXWDTUCERCKIX-UHFFFAOYSA-N

Also Known As

fosmidomycin Fosmidomycina Fosmidomycine Fosmidomycinum Fosmidomicina {3-[formyl(hydroxy)amino]propyl}phosphonic acid 3-(N-hydroxyformamido)propylphosphonic acid 5829E3D9I9 CHEBI:443725 DTXSID70216712

Description

Fosmidomycin is propylphosphonic acid in which one of the hydrogens at position 3 is substituted by a formyl(hydroxy)amino group. An antibiotic obtained from Streptomyces lavendulae, it specifically inhibits DXP reductoisomerase (EC 1.1.1.267), a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. It has a role as an antimicrobial agent, a bacterial metabolite and an EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor. It is a hydroxamic acid and a member of phosphonic acids.

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