methyl (15S,16R,18R)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate

99533-80-9 C27H21N3O5

About methyl (15S,16R,18R)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate

methyl (15S,16R,18R)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate (CAS 99533-80-9) is a chemical compound with the molecular formula C27H21N3O5 and a molecular weight of 467.5 g/mol. It has an InChIKey of KOZFSFOOLUUIGY-SOLYNIJKSA-N.

Properties

methyl (15S,16R,18R)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate molecular structure
CAS Number
99533-80-9
Formula
C27H21N3O5
Molecular Weight
467.5 g/mol
IUPAC Name
methyl (15S,16R,18R)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate
InChI Key
KOZFSFOOLUUIGY-SOLYNIJKSA-N

Also Known As

methyl (15S,16R,18R)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate is also known as k-252a, K252a, Antibiotic K 252a, Antibiotic SF 2370, K 252a, (+)-Antibiotic K 252a, among other names.

k-252a K252a Antibiotic K 252a Antibiotic SF 2370 K 252a IV7H45AM5B K 252 CHEBI:43616 PROTEIN KINASE INHIBITOR K252A methyl (15S,16R,18R)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo(12.11.2.115,18.02,6.07,27.08,13.019,26.020,25)octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate

Description

K-252a is a organic heterooctacyclic compound that is a potent inhibitor of protein kinase C and is isolated from Nocardiopsis sp K-252a. It has a role as an antimicrobial agent, an EC 2.7.11.13 (protein kinase C) inhibitor, a bacterial metabolite and a tropomyosin-related kinase B receptor antagonist. It is a methyl ester, a bridged compound, an organic heterooctacyclic compound and a gamma-lactam.

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