About (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one
(4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one (CAS 76343-93-6) is a chemical compound with the molecular formula C22H31NO5S and a molecular weight of 421.6 g/mol. It has an InChIKey of DDVBPZROPPMBLW-IZGXTMSKSA-N.
Properties
Also Known As
(4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one is also known as latrunculin a, LAT-A, LatA, (+)-latrunculin A, LATRUNCULIN, LATRUNCULIN A (LAT-A), among other names.
Description
Latrunculin A is a bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes. It has a role as a metabolite, a toxin and an actin polymerisation inhibitor. It is a macrolide, an oxabicycloalkane, a thiazolidinone and a cyclic hemiketal.
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