(4R)-4-[(3R,5S,6R,7R,8S,9S… (CAS 459789-99-2)

About (4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid

(4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid (CAS 459789-99-2) is a chemical compound with the molecular formula C26H44O4 and a molecular weight of 420.6 g/mol. It has an InChIKey of ZXERDUOLZKYMJM-ZWECCWDJSA-N.

Properties

CAS Number: 459789-99-2
Formula: C26H44O4
Molecular Weight: 420.6 g/mol
IUPAC Name: (4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
InChI Key: ZXERDUOLZKYMJM-ZWECCWDJSA-N

Also Known As

(4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid is also known as Obeticholic acid, 6-Ethylchenodeoxycholic acid, Ocaliva, 6-Ethyl-CDCA, acido obeticolico, acide obeticholique, among other names.

Obeticholic acid 6-ECDCA INT-747 6-Ethylchenodeoxycholic acid Ocaliva 6-Ethyl-CDCA DSP-1747 INT747 acido obeticolico acide obeticholique

INT 747 6alpha-ethylchenodeoxycholic acid DSP1747 0462Z4S4OZ 6alpha-ethyl-3alpha,7alpha-dihydroxy-5beta-cholan-24-oic acid 6-ethyl-3,7-dihydroxycholan-24-oic acid CHEBI:43602 DTXSID20196671 6-alpha-ethylchenodeoxycholic acid Cholan-24-oic acid, 6-ethyl-3,7-dihydroxy-, (3alpha,5beta,6alpha,7alpha)- (3alpha,5beta,6alpha,7alpha)-6-Ethyl-3,7-dihydroxycholan-24-oic acid (4R)-4-[(1R,3aS,3bS,4R,5R,5aS,7R,9aS,9bS,11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid ObeticholicAcid acidum obeticholicum (4R)-4-((1R,3aS,3bS,4R,5R,5aS,7R,9aS,9bS,11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta(a)phenanthren-1-yl)pentanoic acid RefChem:57128 A05AA04 DTXCID60119162 6-ethyl chenodeoxycholic acid 6ECDCA Obetichloic acid 6alpha-Ethyl-chenodeoxycholic acid (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 6-ETHYL-CHENODEOXYCHOLIC ACID MFCD16621104 UNII-0462Z4S4OZ 6-Et CDCA Obeticholic acid [USAN] Obeticholic acid [USAN:INN] 1osv Ocaliva (TN) 6-Ethylchenodeoxycholic aicd 6-ECDCA; Obeticholic acid OBETICHOLIC ACID [MI] SCHEMBL715823 Obeticholic acid (INT-747) OBETICHOLIC ACID [INN] OBETICHOLIC ACID [JAN] CHEMBL566315 GTPL3435

Description

Obeticholic acid is a dihydroxy-5beta-cholanic acid that is chenodeoxycholic acid carrying an additional ethyl substituent at the 6alpha-position. A semi-synthetic bile acid which acts as a farnesoid X receptor agonist and is used for treatment of primary biliary cholangitis. It has a role as a farnesoid X receptor agonist and a hepatoprotective agent. It is a dihydroxy-5beta-cholanic acid, a 3alpha-hydroxy steroid and a 7alpha-hydroxy steroid. It is functionally related to a chenodeoxycholic acid.

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(4-methyl-2-oxochromen-7-yl) acetate CAS 2747-05-9 (4-nitrophenyl) dihydrogen phosphate CAS 330-13-2 (4-propan-2-ylphenyl)methanol CAS 536-60-7 (4R)-1-methyl-4-prop-1-en-2-ylcyclohexene CAS 5989-27-5 (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one CAS 76343-93-6 (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride CAS 357-08-4 (4R,6R,8R,9Z,11E)-16-chloro-17,19-dihydroxy-4-methyl-3,7-dioxatricyclo[13.4.0.06,8]nonadeca-1(15),9,11,16,18-pentaene-2,13-dione CAS 12772-57-5 (4S,12E)-16,18-dihydroxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),12,15,17-tetraene-2,8-dione CAS 17924-92-4 (5-amino-3,4,6-trihydroxyoxan-2-yl)methyl dihydrogen phosphate (5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methanol CAS 936694-43-8

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(4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid