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(4R,6R,8R,9Z,11E)-16-chloro-17,19-dihydroxy-4-methyl-3,7-dioxatricyclo[13.4.0.06,8]nonadeca-1(15),9,11,16,18-pentaene-2,13-dione

12772-57-5 C18H17ClO6

About (4R,6R,8R,9Z,11E)-16-chloro-17,19-dihydroxy-4-methyl-3,7-dioxatricyclo[13.4.0.06,8]nonadeca-1(15),9,11,16,18-pentaene-2,13-dione

(4R,6R,8R,9Z,11E)-16-chloro-17,19-dihydroxy-4-methyl-3,7-dioxatricyclo[13.4.0.06,8]nonadeca-1(15),9,11,16,18-pentaene-2,13-dione (CAS 12772-57-5) is a chemical compound with the molecular formula C18H17ClO6 and a molecular weight of 364.8 g/mol. It has an InChIKey of WYZWZEOGROVVHK-GTMNPGAYSA-N.

Properties

(4R,6R,8R,9Z,11E)-16-chloro-17,19-dihydroxy-4-methyl-3,7-dioxatricyclo[13.4.0.06,8]nonadeca-1(15),9,11,16,18-pentaene-2,13-dione molecular structure
CAS Number
12772-57-5
Formula
C18H17ClO6
Molecular Weight
364.8 g/mol
IUPAC Name
(4R,6R,8R,9Z,11E)-16-chloro-17,19-dihydroxy-4-methyl-3,7-dioxatricyclo[13.4.0.06,8]nonadeca-1(15),9,11,16,18-pentaene-2,13-dione
InChI Key
WYZWZEOGROVVHK-GTMNPGAYSA-N

Also Known As

(4R,6R,8R,9Z,11E)-16-chloro-17,19-dihydroxy-4-methyl-3,7-dioxatricyclo[13.4.0.06,8]nonadeca-1(15),9,11,16,18-pentaene-2,13-dione is also known as radicicol, Monorden, Monorden A, (+)-Monorden A, Monordene, Monorderne, among other names.

radicicol Monorden Monorden A (+)-Monorden A I60EH8GECX RADICICOL R-2146 Monordene NSC-294404 CHEBI:556075 5-chloro-6-(7,8-epoxy-10-hydroxy-2-oxo-3,5-undecadienyl)-beta-resorcylic acid mu-lactone

Description

Radicicol is an antifungal macrolactone antibiotic, obtained from Diheterospora chlamydosporia and Chaetomium chiversii that inhibits protein tyrosine kinase and heat shock protein 90 (Hsp90). It has a role as a metabolite, an antifungal agent and a tyrosine kinase inhibitor. It is a macrolide antibiotic, an epoxide, a member of phenols, a cyclic ketone, an enone and a member of monochlorobenzenes.

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